62497-68-1
62497-68-1
Chemical Structure
Clonidine-d4
- CAS No.: 62497-68-1
- Formula:C9H5D4Cl2N3
- Molecular Weight:234.12
IUPAC Name: N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-4,4,5,5-d4-2-amine
InChIKey: GJSURZIOUXUGAL-CQOLUAMGSA-N
SMILES: ClC(C=CC=C1Cl)=C1NC2=NC([2H])([2H])C([2H])([2H])N2
Biological Activity: Clonidine-d4 is the deuterium labeled Clonidine. Clonidine hydrochloride is an agonist of α2-adrenoceptor and potent antihypertensive agent[1][2][3][4][5].
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Clonidine-d4 | Clonidine-d4 is the deuterium labeled Clonidine. Clonidine hydrochloride is an agonist of α2-adrenoceptor and potent antihypertensive agent. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Bugajski J, et al. The involvement of central alpha-adrenergic and histamine H2-receptors in the hypothermia induced by clonidine in the rat. Neuropharmacology. 1980 Jan;19(1):9-15.;Zhang YM, et al. Clonidine induces calcitonin gene-related peptide expres [Content Brief]
Keywords
