TMEM68 - transmembrane protein 68 Gene
Species: Homo sapiens
About TMEM68
This gene has 18 transcripts (splice variants) and 283 orthologues. Ubiquitous expression in thyroid (RPKM 4.7), prostate (RPKM 3.9) and 25 other tissues.
Summary
Predicted to enable Acyltransferase activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
TMEM68 Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001286657.2 | NP_001273586.1 | transmembrane protein 68 isoform 1 |
| NM_001286660.2 | NP_001273589.1 | transmembrane protein 68 isoform 3 |
| NM_001286661.2 | NP_001273590.1 | transmembrane protein 68 isoform 4 |
| NM_001363176.1 | NP_001350105.1 | transmembrane protein 68 isoform 1 |
| NM_001363177.1 | NP_001350106.1 | transmembrane protein 68 isoform 5 |
| NM_152417.3 | NP_689630.1 | transmembrane protein 68 isoform 2 |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables phospholipid:diacylglycerol acyltransferase activity |
IDA
IDA: Inferred from direct assay
|
37648867 | GOA |
| Biological Process GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| involved in triglyceride biosynthetic process |
IDA
IDA: Inferred from direct assay
|
37648867 | GOA |
| Cellular Component GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| is active in endoplasmic reticulum membrane |
IDA
IDA: Inferred from direct assay
|
37648867 | GOA |
TMEM68 Protein Structure
Acyltransferase: Acyltransferase (111 - 235)
- 0
- 100
- 200
- 300
- 324 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
transmembrane protein 68 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Freemartinism |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Felis catus | TMEM68 | VGNC | VGNC:66359 |
| Mus musculus | TMEM68 | MGD | MGI:1919348 |
| Canis familiaris | TMEM68 | VGNC | VGNC:47600 |
| Bos taurus | TMEM68 | VGNC | VGNC:36107 |
| Macaca mulatta | TMEM68 | VGNC | VGNC:79618 |
| Rattus norvegicus | TMEM68 | RGD | RGD:1309006 |
| Others | TMEM68 | NCBI |