ARMC3 - armadillo repeat containing 3 Gene
Also Known as CT81; KU-CT-1
Species: Homo sapiens
About ARMC3
This gene has 13 transcripts (splice variants), 195 orthologues and 4 paralogues. Restricted expression toward testis (RPKM 12.8).
Summary
Armadillo/beta-catenin (CTNNB1; MIM 116806)-like (ARM) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis (Li et al., 2006 [PubMed 16915934]).[supplied by OMIM, Mar 2008]
ARMC3 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001282745.2 | NP_001269674.1 | armadillo repeat-containing protein 3 isoform 2 |
| NM_001282746.2 | NP_001269675.1 | armadillo repeat-containing protein 3 isoform 3 |
| NM_001282747.2 | NP_001269676.1 | armadillo repeat-containing protein 3 isoform 4 |
| NM_173081.5 | NP_775104.2 | armadillo repeat-containing protein 3 isoform 1 |
ARMC3 Protein Structure
Arm: Armadillo/beta-catenin-like repeat (57 - 89)
HEAT_2: HEAT repeats (152 - 245)
HEAT_2: HEAT repeats (276 - 381)
Arm: Armadillo/beta-catenin-like repeat (387 - 426)
Arm: Armadillo/beta-catenin-like repeat (471 - 503)
EDR1: Ethylene-responsive protein kinase Le-CTR1 (737 - 859)
- 0
- 200
- 400
- 600
- 800
- 872 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
armadillo repeat-containing protein 3 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Macular Degeneration, Age-Related, 4 |
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| Currarino Syndrome |
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