Spint2 - serine peptidase inhibitor, Kunitz type, 2 Gene

Also Known as Pb; HAI-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 292770

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in cellular response to BMP stimulus and negative regulation of neural precursor cell proliferation. Located in plasma membrane. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 3. Orthologous to human SPINT2 (serine peptidase inhibitor, Kunitz type 2). [provided by Alliance of Genome Resources, Apr 2022]

Spint2 Products (2)

mRNA Protein Name
NM_001082549.1 NP_001076018.1 kunitz-type protease inhibitor 2 isoform a precursor
NM_199087.1 NP_954518.1 kunitz-type protease inhibitor 2 isoform b precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Références Source
involved in cellular response to BMP stimulus IEP
IEP: Inferred from expression pattern
23409135 RGD
involved in negative regulation of neural precursor cell proliferation IMP
IMP: Inferred from mutant phenotype
23409135 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kunitz-type protease inhibitor 2

  • hepatocyte growth factor activator inhibitor type 2

  • placental bikunin

  • serine protease inhibitor, Kunitz type 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS13686 SPINT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19530 Spint2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26025 Spint2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spint2 NCBI NCBI:10653
Mus musculus Spint2 NCBI NCBI:20733