Slc9a9 - solute carrier family 9 (sodium/hydrogen exchanger), member 9 Gene
Also Known as Nhe9; 9930105B05; 5730527A11Rik
Species: Mus musculus
Summary
Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to act upstream of or within ion transport. Predicted to be located in endosome and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane and recycling endosome. Is expressed in several structures, including ear; hemolymphoid system; nervous system; tail somite; and urinary system. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human SLC9A9 (solute carrier family 9 member A9). [provided by Alliance of Genome Resources, Apr 2022]
Slc9a9 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_177909.5 | NP_808577.3 | sodium/hydrogen exchanger 9 |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables potassium:proton antiporter activity |
IDA
IDA: Inferred from direct assay
|
17005858 | MGI |
| enables sodium:proton antiporter activity |
IDA
IDA: Inferred from direct assay
|
17005858 | MGI |
| Biological Process GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| involved in defense response to bacterium |
IDA
IDA: Inferred from direct assay
|
35716776 | MGI |
| involved in phagosome maturation |
IDA
IDA: Inferred from direct assay
|
35716776 | MGI |
| involved in potassium ion transmembrane transport |
IDA
IDA: Inferred from direct assay
|
17005858 | MGI |
| involved in regulation of intracellular pH |
IDA
IDA: Inferred from direct assay
|
17005858 | MGI |
| involved in sodium ion transmembrane transport |
IDA
IDA: Inferred from direct assay
|
17005858 | MGI |
| Cellular Component GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| located in early phagosome |
IDA
IDA: Inferred from direct assay
|
35716776 | MGI |
| located in phagocytic vesicle membrane |
IDA
IDA: Inferred from direct assay
|
35716776 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
17005858 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sodium/hydrogen exchanger 9 |
|