New humantenine-type alkaloids from Gelsemium elegans

  • J Nat Prod. 1989 May-Jun;52(3):588-94. doi: 10.1021/np50063a019.
L Z Lin  1 ,  G A Cordell ,  C Z Ni ,  J Clardy
Affiliations
  • 1. Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois, Chicago 60612.
PMID: 2778451 DOI: 10.1021/np50063a019
Abstract

The alkaloid extract of the whole plant of Gelsemium elegans has afforded four new alkaloids: N-desmethoxyrankinidine [1], 11-hydroxrankinidine [3], 11-hydroxyhuman-humantenine [4] and humantenirine [6]. The structures of 5 was established through X-ray crystallographic analysis, and the structures of the Other three new Alkaloids were deduced by spectral analysis (1H, 13C, APT, 2D-COSY and 2D-HETCOR).

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