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3103886-80-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3103886-80-9" in MCE Product Catalog:

RIPK1-IN-35
RIPK1-IN-35
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Cat. No.: HY-178762S
CAS No.: 3103886-96-7
RIPK1-IN-35 is a selective and orally active RIPK1 inhibitor with an IC50 of 5.33 nM. RIPK1-IN-35 has a potent protective effect against necroptosis in both human and murine cells. RIPK1-IN-35 shows good therapeutic effects in both TNF-α-induced systemic inflammatory response syndrome and DSS (HY-116282C)-induced inflammatory bowel disease models. RIPK1-IN-35 can be used to the study of inflammatory diseases related to necroptosis .
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