2857982-35-3
2857982-35-3
Chemical Structure
TTBK1/2-IN-2
- CAS. Nr.: 2857982-35-3
- Formula:C22H24N4O
- Molecular Weight:360.45
SMILES: OC(CC)(CC)C#CC1=CC2=C(NC3=C2C4=C(C=NC(N)=N4)CCC3)C=C1
Biological Activity: TTBK1/2-IN-2 (compound 9) is a potent Tau tubulin kinase 1 (TTBK1) and TTBK2 inhibitor with IC50s of 384 nM and 175 nM, respectively. TTBK1/2-IN-2 shows a significant ciliogenesis phenotype in human induced pluripotent stem cells (iPSCs)[1].
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TTBK1/2-IN-2 | TTBK1/2-IN-2 (compound 9) is a potent Tau tubulin kinase 1 (TTBK1) and TTBK2 inhibitor with IC50s of 384 nM and 175 nM, respectively. TTBK1/2-IN-2 shows a significant ciliogenesis phenotype in human induced pluripotent stem cells (iPSCs). | |||||||||||||||||||||
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References
Keywords
