SMCO1 - single-pass membrane protein with coiled-coil domains 1 Gene

Also Known as C3orf43

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 255798

About SMCO1

This gene has 2 transcripts (splice variants) and 103 orthologues. Restricted expression toward heart (RPKM 14.0).

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SMCO1 Products (2)

mRNA	Protein	Name
NM_001077657.3	NP_001071125.1	single-pass membrane and coiled-coil domain-containing protein 1 isoform 1
NM_001320473.2	NP_001307402.1	single-pass membrane and coiled-coil domain-containing protein 1 isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Verweise	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SMCO1 Protein Structure

DUF4547

0
100
200
214 a.a.

Protein Preferred Names	Protein Names
single-pass membrane and coiled-coil domain-containing protein 1

SMCO1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Verweise
Intra	SMCO1	Q147U7	FNDC8	Homo sapiens	Q8TC99	Y2H Array	32296183
Intra	SMCO1	Q147U7	FNDC8	Homo sapiens	Q8TC99	Y2H Prey Pooling	32296183
Intra	SMCO1	Q147U7	FNDC8	Homo sapiens	Q8TC99	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Subvalvular Aortic Stenosis	Fixed Subaortic Stenosis Subaortic Stenosis Aortic Stenosis, Subvalvular
Chromosome 3q29 Deletion Syndrome	Chromosome 3q29 Microdeletion Syndrome 3q29 Microdeletion Syndrome 3q Subtelomere Deletion Syndrome 3q29 Recurrent Deletion 3qter Deletion 3q29 Deletion Syndrome Monosomy 3q29 Microdeletion 3q29 Syndrome Del(3)(Q29) Monosomy 3qter 3q29 Deletion Del3q29
Immunodeficiency 46	Tfrc-Related Combined Immunodeficiency IMD46 Cid Due To Tfrc Deficiency Combined Immunodeficiency Due To Tfrc Deficiency
Meningocele	Isolated Spina Bifida Spina Bifida Cleft Spine Open Spine Rachischisis Spinal Dysraphism Spinal Meningocele Congenital Meningocele
Nephronophthisis 3	NPHP3 Nph3 Adolescent Nephronophthisis Nephronophthisis, Type 3

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-RS13424	SMCO1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SMCO1	VGNC	VGNC:102846
Canis familiaris	SMCO1	VGNC	VGNC:46549
Bos taurus	SMCO1	VGNC	VGNC:35005
Rattus norvegicus	SMCO1	RGD	RGD:1562500
Mus musculus	SMCO1	MGD	MGI:1916826