Figla - folliculogenesis specific basic helix-loop-helix Gene

Also Known as bHLHc8; FIGalpha

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26910

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Is expressed in follicle cell of primary follicle; oocyte of primary follicle; oocyte of secondary follicle; and ovary. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 6. Orthologous to human FIGLA (folliculogenesis specific bHLH transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Figla Products (1)

mRNA Protein Name
NM_012013.2 NP_036143.1 factor in the germline alpha

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
9362457 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
9362457 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9362457 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

factor in the germline alpha

  • FIG alpha

  • transcription factor FIGa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS04945 FIGLA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Figla NCBI NCBI:344018