Apom - apolipoprotein M Gene

Also Known as G3a; NG20; 1190010O19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 55938

Summary

Enables antioxidant activity. Involved in several processes, including Cholesterol efflux; high-density lipoprotein particle clearance; and plasma lipoprotein particle organization. Acts upstream of or within lipoprotein metabolic process and reverse Cholesterol transport. Located in extracellular region. Part of discoidal high-density lipoprotein particle. Is expressed in several structures, including gut; liver; male reproductive gland or organ; and urinary system. Human ortholog(s) of this gene implicated in coronary artery disease; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human APOM (Apolipoprotein M). [provided by Alliance of Genome Resources, Apr 2022]

Apom Products (1)

mRNA Protein Name
NM_018816.2 NP_061286.1 apolipoprotein M precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables antioxidant activity IDA
IDA: Inferred from direct assay
22204862 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16099815 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in cholesterol efflux IMP
IMP: Inferred from mutant phenotype
15793583 MGI
involved in high-density lipoprotein particle assembly IMP
IMP: Inferred from mutant phenotype
15793583 MGI
involved in high-density lipoprotein particle clearance IMP
IMP: Inferred from mutant phenotype
15793583 MGI
involved in high-density lipoprotein particle remodeling IMP
IMP: Inferred from mutant phenotype
15793583 MGI
acts upstream of or within lipoprotein metabolic process IMP
IMP: Inferred from mutant phenotype
15793583 MGI
involved in negative regulation of plasma lipoprotein oxidation IDA
IDA: Inferred from direct assay
22204862 MGI
acts upstream of or within reverse cholesterol transport IMP
IMP: Inferred from mutant phenotype
15793583 MGI
Cellular Component GO Annotation Evidence Verweise Source
part of discoidal high-density lipoprotein particle IDA
IDA: Inferred from direct assay
15793583 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
15793583 MGI
part of high-density lipoprotein particle IDA
IDA: Inferred from direct assay
22204862 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

apolipoprotein M

  • apo-M

Recombinant Apom Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P72297 Apolipoprotein M/APOM Protein, Mouse (P.pastoris, His) Q9Z1R3 (M1-K190) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS00860 APOM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18228 Apom Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24707 Apom Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Apom NCBI NCBI:55937