DEPP1 - DEPP autophagy regulator 1 Gene

Also Known as FIG; DEPP; Fseg; C10orf10

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11067

About DEPP1

Cytogenetic location: 10q11.21 Genomic coordinates (GRCh38): 10:44,976,128-44,978,809 (from NCBI)

This gene has 3 transcripts (splice variants) and 88 orthologues. Broad expression in fat (RPKM 86.3), endometrium (RPKM 51.4) and 24 other tissues.

Summary

The expression of this gene is induced by fasting as well as by progesterone. The protein encoded by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology domain and a peroxisomal targeting signal. Production of the encoded protein leads to phosphorylation and activation of the transcription factor ELK1. [provided by RefSeq, Jul 2008]

DEPP1 Products (1)

mRNA Protein Name
NM_007021.4 NP_008952.1 protein DEPP1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of autophagy IDA
IDA: Inferred from direct assay
28545464 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25261981 GOA
located in mitochondrion IDA
IDA: Inferred from direct assay
25261981 GOA
located in peroxisome IDA
IDA: Inferred from direct assay
25261981 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DEPP1 Protein Structure

DEPP

DEPP: Decidual protein induced by progesterone family (25 - 212)

  • 0
  • 100
  • 200
  • 212 a.a.
Protein Preferred Names Protein Names

protein DEPP1

  • DEPP1 autophagy regulator

Related Diseases

Diseases Alias
Colon Sarcoma

  • Colonic Sarcoma
Gastric Leiomyoma

  • Leiomyoma Of The Stomach
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03696 DEPP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus DEPP1 MGD MGI:1918730
Rattus norvegicus DEPP1 RGD RGD:1565700
Canis familiaris DEPP1 VGNC VGNC:49591
Macaca mulatta DEPP1 VGNC VGNC:71693
Bos taurus DEPP1 VGNC VGNC:49544