Gpc4 - glypican 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 317322

Summary

Involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane and regulation of presynapse assembly. Is active in glutamatergic synapse. Is anchored component of presynaptic membrane. Human ortholog(s) of this gene implicated in Keipert syndrome. Orthologous to human GPC4 (glypican 4). [provided by Alliance of Genome Resources, Apr 2022]

Gpc4 Products (1)

mRNA Protein Name
NM_001014108.1 NP_001014130.1 glypican-4 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
22722203 RGD
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IMP
IMP: Inferred from mutant phenotype
22722203 RGD
involved in regulation of presynapse assembly IDA
IDA: Inferred from direct assay
23911103 RGD
involved in regulation of presynapse assembly IMP
IMP: Inferred from mutant phenotype
23911103 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
22722203 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
22722203 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
23911103 RGD
is active in presynaptic membrane IMP
IMP: Inferred from mutant phenotype
23911103 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glypican-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05629 GPC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpc4 NCBI NCBI:2239