CYP2W1 - cytochrome P450 family 2 subfamily W member 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54905

About CYP2W1

Cytogenetic location: 7p22.3 Genomic coordinates (GRCh38): 7:983,181-989,640 (from NCBI)

This gene has 5 transcripts (splice variants), 107 orthologues and 15 paralogues. Biased expression in skin (RPKM 2.9), duodenum (RPKM 2.7) and 8 other tissues.

Summary

This gene encodes a member of the Cytochrome P450 superfamily of Enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and Other lipids. [provided by RefSeq, Jul 2008]

CYP2W1 Products (1)

mRNA Protein Name
NM_017781.3 NP_060251.2 cytochrome P450 2W1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables all-trans retinal binding IDA
IDA: Inferred from direct assay
26936974 GOA
enables all-trans-retinol binding IDA
IDA: Inferred from direct assay
26936974 GOA
enables retinoic acid 4-hydroxylase activity IDA
IDA: Inferred from direct assay
26936974 GOA
enables retinoic acid binding IDA
IDA: Inferred from direct assay
26936974 GOA
Biological Process GO Annotation Evidence References Source
involved in aflatoxin metabolic process IDA
IDA: Inferred from direct assay
16551781 GOA
involved in phospholipid metabolic process IDA
IDA: Inferred from direct assay
22591743 GOA
involved in retinoic acid catabolic process IDA
IDA: Inferred from direct assay
26936974 GOA
involved in xenobiotic metabolic process IDA
IDA: Inferred from direct assay
16551781 GOA
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
20805301 GOA
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
20805301 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CYP2W1 Protein Structure

p450

p450: Cytochrome P450 (32 - 483)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 490 a.a.
Protein Preferred Names Protein Names

cytochrome P450 2W1

  • CYPIIW1

CYP2W1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810254 CYP2W1 Antibody (YA9598) WB, ICC/IF, IF-Tissue, IP, ELISA human

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03469 CYP2W1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CYP2W1 VGNC VGNC:81300
Felis catus CYP2W1 VGNC VGNC:103323
Canis familiaris CYP2W1 VGNC VGNC:50358
Rattus norvegicus CYP2W1 RGD RGD:1305193
Bos taurus CYP2W1 VGNC VGNC:110263
Mus musculus CYP2W1 MGD MGI:3616076