2097002-61-2
2097002-61-2
Chemical Structure
Selitrectinib
Synonym(s): LOXO-195
- CAS No.: 2097002-61-2
- Formula:C20H21FN6O
- Molecular Weight:380.42
IUPAC Name: (13E,14E,22R,6R)-35-fluoro-6-methyl-7-aza-1(5,3)-pyrazolo[1,5-a]pyrimidina-3(3,2)-pyridina-2(1,2)-pyrrolidinacyclooctaphan-8-one
InChIKey: OEBIHOVSAMBXIB-SJKOYZFVSA-N
SMILES: FC1=CN=C(CC[C@H](N2)C)C([C@](CCC3)([H])N3C(C=CN4N=C5)=NC4=C5C2=O)=C1
Biological Activity: Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor, with IC50s of 0.6 nM and <2.5 nM for TRKA and TRKC, respectively[1].
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Selitrectinib | 99.74% | Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor, with IC50s of 0.6 nM and <2.5 nM for TRKA and TRKC, respectively. | ||||||||||||||||||||
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Selitrectinib (Standard) | ≥98% | Selitrectinib (Standard) is the analytical standard of Selitrectinib. This product is intended for research and analytical applications. Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor, with IC50s of 0.6 nM and <2.5 nM for TRKA and TRKC, respectively. | ||||||||||||||||||||
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References
