914357-88-3
Chemical Structure
FtsZ-IN-13
- CAS No.: 914357-88-3
- Formula:C18H14N2O4S2
- Molecular Weight:386.44
InChIKey: JJIKZEXOBUFQGZ-UHFFFAOYSA-N
SMILES: O=S1(C2=CC=CC=C2C(SC3=NN=C(O3)CC4=CC=C(C=C4)OC)=C1)=O
Biological Activity: FtsZ-IN-13 (Compound C11) is an inhibitor of temperature-sensitive mutant Z (FtsZ), with IC50 values of 47.97, 34 μM against FtsZSa and FtsZPa, respectively. FtsZ-IN-13 has a notable antimicrobial activity against S. aureus (minimum inhibitory concentration value of 2 μg/mL), cystic fibrosis S. aureus clinical isolates, and methicillin-resistant S. aureus (MRSA) strains. FtsZ-IN-13 can be used for antimicrobial resistance study[1].
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FtsZ-IN-13 | FtsZ-IN-13 (Compound C11) is an inhibitor of temperature-sensitive mutant Z (FtsZ), with IC50 values of 47.97, 34 μM against FtsZSa and FtsZPa, respectively. FtsZ-IN-13 has a notable antimicrobial activity against S. aureus (minimum inhibitory concentration value of 2 μg/mL), cystic fibrosis S. aureus clinical isolates, and methicillin-resistant S. aureus (MRSA) strains. FtsZ-IN-13 can be used for antimicrobial resistance study. | |||||||||||||||||||||
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Keywords
