ABI3BP - ABI family member 3 binding protein Gene

Also Known as TARSH; NESHBP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25890

About ABI3BP

Cytogenetic location: 3q12.2 Genomic coordinates (GRCh38): 3:100,749,156-100,993,421 (from NCBI)

This gene has 28 transcripts (splice variants), 268 orthologues and 1 paralogue. Broad expression in gall bladder (RPKM 33.8), lung (RPKM 26.2) and 21 other tissues.

Summary

Predicted to enable actin filament binding activity and glycosaminoglycan binding activity. Predicted to be involved in regulation of actin Cytoskeleton reorganization; regulation of dendritic spine morphogenesis; and regulation of postsynaptic density assembly. Predicted to act upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in extracellular space. Colocalizes with collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

ABI3BP Products (11)

mRNA Protein Name
NM_001349329.2 NP_001336258.2 target of Nesh-SH3 isoform 1 precursor
NM_001349330.2 NP_001336259.2 target of Nesh-SH3 isoform 2 precursor
NM_001349331.2 NP_001336260.2 target of Nesh-SH3 isoform 3 precursor
NM_001349332.2 NP_001336261.2 target of Nesh-SH3 isoform 4 precursor
NM_001365642.2 NP_001352571.2 target of Nesh-SH3 isoform 6 precursor
NM_001365643.2 NP_001352572.2 target of Nesh-SH3 isoform 7 precursor
NM_001375547.2 NP_001362476.1 target of Nesh-SH3 isoform 8 precursor
NM_001375549.2 NP_001362478.1 target of Nesh-SH3 isoform 9 precursor
NM_001375550.1 NP_001362479.1 target of Nesh-SH3 isoform 10 precursor
NM_001377332.1 NP_001364261.1 target of Nesh-SH3 isoform 11 precursor
NM_015429.4 NP_056244.3 target of Nesh-SH3 isoform 5 precursor

ABI3BP Protein Structure

fn3

fn3: Fibronectin type III domain (840 - 921)

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  • 1000
  • 1075 a.a.
Protein Preferred Names Protein Names

target of Nesh-SH3

  • ABI family, member 3 (NESH) binding protein

Related Diseases

Diseases Alias
Benign Pleural Mesothelioma

  • Mesothelioma Of Pleura

  • Benign Neoplasm Of Mesothelial Tissue Of Pleura

  • Pleural Malignant Mesothelioma
Agnathia-Otocephaly Complex

  • Otocephaly

  • Holoprosencephaly-Agnathia

  • Dysgnathia Complex Agnathia-Holoprosencephaly

  • AGOTC

  • Agnathia-Holoprosencephaly-Situs Inversus Syndrome

  • Dysgnathia Complex

  • Agnathia-Holoprosencephaly

  • Cervical Auricle
Fibrochondrogenesis

  • Fbcg1

  • Fbcg2

  • Fibrochondrogenesis-1

  • Fibrochondrogenesis-2

  • Fibrochondrogenesis 1

  • Fibrochondrogenesis 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS00101 ABI3BP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ABI3BP VGNC VGNC:37477
Felis catus ABI3BP VGNC VGNC:59489
Rattus norvegicus ABI3BP RGD RGD:1562717
Macaca mulatta ABI3BP VGNC VGNC:81175
Mus musculus ABI3BP MGD MGI:2444583