Scmh1 - sex comb on midleg homolog 1 Gene

Also Known as Scml1; Scml3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 29871

Summary

Predicted to enable chromatin binding activity and histone binding activity. Acts upstream of or within anterior/posterior pattern specification; chromatin remodeling; and spermatogenesis. Located in chromocenter and nucleus. Is expressed in several structures, including branchial arch; genitourinary system; gut; limb; and nervous system. Orthologous to human SCMH1 (Scm polycomb group protein homolog 1). [provided by Alliance of Genome Resources, Apr 2022]

Scmh1 Products (8)

mRNA Protein Name
NM_001159630.2 NP_001153102.1 polycomb protein SCMH1 isoform 2
NM_001379184.1 NP_001366113.1 polycomb protein SCMH1 isoform 4
NM_001379185.1 NP_001366114.1 polycomb protein SCMH1 isoform 1
NM_001379186.1 NP_001366115.1 polycomb protein SCMH1 isoform 3
NM_001404090.1 NP_001391019.1 polycomb protein SCMH1 isoform 2
NM_001404102.1 NP_001391031.1 polycomb protein SCMH1 isoform 5
NM_001404103.1 NP_001391032.1 polycomb protein SCMH1 isoform 6
NM_013883.3 NP_038911.1 polycomb protein SCMH1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
10653359 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
17215307 MGI
acts upstream of or within chromatin remodeling IMP
IMP: Inferred from mutant phenotype
17215307 MGI
acts upstream of or within spermatogenesis IGI
IGI: Inferred from genetic interaction
17215307 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
17215307 MGI
Cellular Component GO Annotation Evidence Références Source
located in chromocenter IDA
IDA: Inferred from direct assay
17215307 MGI
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
17215307 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polycomb protein SCMH1

  • sex comb on midleg 1

  • sex comb on midleg-like 1

  • sex comb on midleg-like 3

Scmh1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
Scmh1 Q8K214 Phc1 Mus musculus Q64028
Pull Down
10653359
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS12515 SCMH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scmh1 NCBI NCBI:22955