Gusb - glucuronidase, beta Gene

Also Known as Gus-s; Ac2-223

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24434

Summary

Enables beta-glucuronidase activity and carbohydrate binding activity. Predicted to be involved in glucuronoside catabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Located in lysosome. Biomarker of mucopolysaccharidosis and peritonitis. Human ortholog(s) of this gene implicated in Sly syndrome. Orthologous to human GUSB (glucuronidase beta). [provided by Alliance of Genome Resources, Apr 2022]

Gusb Products (1)

mRNA Protein Name
NM_017015.3 NP_058711.3 beta-glucuronidase precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables beta-glucuronidase activity IDA
IDA: Inferred from direct assay
3355537 RGD
enables beta-glucuronidase activity IMP
IMP: Inferred from mutant phenotype
8717430 RGD
enables carbohydrate binding IDA
IDA: Inferred from direct assay
8702598 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-glucuronidase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05927 GUSB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20750 Gusb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27262 Gusb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gusb NCBI NCBI:2990