Ffar1 - free fatty acid receptor 1 Gene

Also Known as Gpr40

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 266607

Summary

Enables fatty acid binding activity. Involved in G protein-coupled receptor signaling pathway; positive regulation of calcium ion transport into cytosol; and positive regulation of Insulin secretion. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FFAR1 (Free Fatty Acid Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ffar1 Products (1)

mRNA Protein Name
NM_153304.2 NP_695216.1 free fatty acid receptor 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables fatty acid binding IDA
IDA: Inferred from direct assay
12496284 RGD
Biological Process GO Annotation Evidence References Source
involved in G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12496284 RGD
involved in positive regulation of calcium ion transport into cytosol IMP
IMP: Inferred from mutant phenotype
15914509 RGD
involved in positive regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
16081037 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

free fatty acid receptor 1

  • G-protein coupled receptor 40

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153667 MK-2305 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ffar1 NCBI NCBI:2864