Mgat4a - mannoside acetylglucosaminyltransferase 4, isoenzyme A Gene

Also Known as GnT-IVa; glcNAc-T-IVa; 9530018I07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 269181

Summary

Enables acetylglucosaminyltransferase activity. Acts upstream of or within protein N-linked glycosylation. Predicted to be located in Golgi apparatus; extracellular region; and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi stack; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and respiratory system. Orthologous to human MGAT4A (alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A). [provided by Alliance of Genome Resources, Apr 2022]

Mgat4a Products (2)

mRNA Protein Name
NM_001290801.1 NP_001277730.1 alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform 2
NM_173870.3 NP_776295.1 alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables acetylglucosaminyltransferase activity IDA
IDA: Inferred from direct assay
20015870 MGI
enables alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity IDA
IDA: Inferred from direct assay
16377570 MGI
enables glycosyltransferase activity IDA
IDA: Inferred from direct assay
24619415 MGI
Biological Process GO Annotation Evidence References Source
involved in N-glycan processing IDA
IDA: Inferred from direct assay
16377570 MGI
acts upstream of or within protein N-linked glycosylation IGI
IGI: Inferred from genetic interaction
20015870 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

  • N-acetylglucosaminyltransferase IVa

  • N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa

  • UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08404 MGAT4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-E70297 N-Acetylglucosaminyltransferase IVa / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mgat4a NCBI NCBI:11320