Aspm - assembly factor for spindle microtubules Gene

Also Known as Calmbp1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 289054

Summary

Predicted to enable Calmodulin binding activity. Predicted to be involved in regulation of meiotic cell cycle; spindle localization; and spindle organization. Predicted to act upstream of or within several processes, including gamete generation; maintenance of centrosome location; and nervous system development. Located in apical plasma membrane; microtubule cytoskeleton; and midbody. Human ortholog(s) of this gene implicated in microcephaly; primary autosomal recessive microcephaly; primary autosomal recessive microcephaly 5; and visual epilepsy. Orthologous to human ASPM (assembly factor for spindle microtubules). [provided by Alliance of Genome Resources, Apr 2022]

Aspm Products (1)

mRNA Protein Name
NM_001105955.2 NP_001099425.2 abnormal spindle-like microcephaly-associated protein

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
17534152 RGD
located in centrosome IDA
IDA: Inferred from direct assay
17534152 RGD
located in midbody IDA
IDA: Inferred from direct assay
17534152 RGD
located in mitotic spindle pole IDA
IDA: Inferred from direct assay
17534152 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

abnormal spindle-like microcephaly-associated protein

  • abnormal spindle microtubule assembly

  • asp (abnormal spindle) homolog, microcephaly associated

  • asp (abnormal spindle)-like, microcephaly associated

  • calmodulin binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01104 ASPM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21296 Aspm Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27815 Aspm Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aspm NCBI NCBI:259266