Htra3 - HtrA serine peptidase 3 Gene

Also Known as Prsp; Tasp; 2210021K23Rik; 9530081K03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 78558

Summary

Enables serine-type peptidase activity. Involved in negative regulation of BMP signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway; and proteolysis. Predicted to be located in extracellular region. Is expressed in decidua; decidua basalis; and decidua capsularis. Orthologous to human HTRA3 (HtrA serine peptidase 3). [provided by Alliance of Genome Resources, Apr 2022]

Htra3 Products (2)

mRNA Protein Name
NM_001042615.2 NP_001036080.1 serine protease HTRA3 isoform b precursor
NM_030127.3 NP_084403.2 serine protease HTRA3 isoform a precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15206957 MGI
enables serine-type peptidase activity IDA
IDA: Inferred from direct assay
15206957 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of BMP signaling pathway IDA
IDA: Inferred from direct assay
15206957 MGI
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: Inferred from direct assay
15206957 MGI
involved in proteolysis IDA
IDA: Inferred from direct assay
15206957 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine protease HTRA3

  • high-temperature requirement factor A3

  • pregnancy-related serine protease

  • probable serine protease HTRA3

  • toll-associated serine protease

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01891 CAPN5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06488 HTRA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27386 Capn5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Htra3 NCBI NCBI:94031