773852-25-8
773852-25-8
Chemical Structure
103D5R
- CAS No.: 773852-25-8
- Formula:C20H21N3O2
- Molecular Weight:335.40
IUPAC Name: 1-(1-(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethyl)-1H-imidazo[4,5-b]pyridine
InChIKey: MCVWPJZBARCDLJ-UHFFFAOYSA-N
SMILES: CC(N1C=NC2=NC=CC=C21)C3=CC=C4C(C=CC(C)(C)O4)=C3OC
Biological Activity: 103D5R (Compound 15) is an inhibitor for the activation of hypoxia-inducible factor-1 (HIF-1) with an IC50 of 35 µM, through reduction of the HIF-1α protein synthesis. 103D5R inhibits the proliferation of LN229 with IC50 of 26 µM[1].
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103D5R | 103D5R (Compound 15) is an inhibitor for the activation of hypoxia-inducible factor-1 (HIF-1) with an IC50 of 35 µM, through reduction of the HIF-1α protein synthesis. 103D5R inhibits the proliferation of LN229 with IC50 of 26 µM. | |||||||||||||||||||||
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References
Keywords
