Bsx - brain specific homeobox Gene

Also Known as Bsx1a; Bsx1b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 244813

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including eating behavior; mammary gland involution; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in brain; metanephros; and renal vasculature. Orthologous to human BSX (brain specific homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Bsx Products (1)

mRNA Protein Name
NM_178245.3 NP_839976.1 brain-specific homeobox protein homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
17353277 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
17353277 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17550780 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
17550780 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within eating behavior IMP
IMP: Inferred from mutant phenotype
17550780 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
17550780 MGI
acts upstream of or within mammary gland involution IMP
IMP: Inferred from mutant phenotype
17485440 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17550780 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17353277 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
17550780 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
17550780 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
17550780 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

brain-specific homeobox protein homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01650 BSX Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bsx NCBI NCBI:390259