Gjb1 - gap junction protein, beta 1 Gene

Also Known as Cx32; Cxng

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29584

Summary

Enables gap junction channel activity. Involved in epididymis development and purine ribonucleotide transport. Located in gap junction and lateral plasma membrane. Part of protein-containing complex. Biomarker of autoimmune thyroiditis and extrahepatic cholestasis. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked dominant 1. Orthologous to human GJB1 (Gap Junction Protein beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Gjb1 Products (1)

mRNA Protein Name
NM_017251.2 NP_058947.1 gap junction beta-1 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables gap junction channel activity IDA
IDA: Inferred from direct assay
12119284 RGD
Biological Process GO Annotation Evidence References Source
involved in epididymis development IEP
IEP: Inferred from expression pattern
12388089 RGD
involved in purine ribonucleotide transport IDA
IDA: Inferred from direct assay
12119284 RGD
Cellular Component GO Annotation Evidence References Source
located in gap junction IDA
IDA: Inferred from direct assay
12119284 RGD
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
12388089 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
15817491 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction beta-1 protein

  • GAP junction 28 kDa liver protein

  • connexin g

  • connexin-32

  • gap junction membrane channel protein beta 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05446 GJB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjb1 NCBI NCBI:2705