Tbx2 - T-box transcription factor 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 303398

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cardiac jelly development; circulatory system development; and embryonic morphogenesis. Predicted to act upstream of or within several processes, including animal organ development; muscle cell fate determination; and ureteric peristalsis. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in vertebral anomalies and variable endocrine and T-cell dysfunction. Orthologous to human TBX2 (T-box transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tbx2 Products (1)

mRNA Protein Name
NM_001401806.1 NP_001388735.1 T-box transcription factor TBX2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to dexamethasone stimulus IEP
IEP: Inferred from expression pattern
36790081 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-box transcription factor TBX2

  • T-box 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14275 TBX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22339 Tbx2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28861 Tbx2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tbx2 NCBI NCBI:6909