Nek4 - NIMA-related kinase 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 306252

Summary

Predicted to enable manganese ion binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including positive regulation of transcription, DNA-templated; protein phosphorylation; and regulation of cellular response to stress. Located in ciliary plasm; ciliary transition zone; and Cytoskeleton. Orthologous to human NEK4 (NIMA related kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Nek4 Products (1)

mRNA Protein Name
NM_001013134.2 NP_001013152.2 serine/threonine-protein kinase Nek4

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in ciliary basal body IDA
IDA: Inferred from direct assay
21685204 RGD
located in ciliary plasm IDA
IDA: Inferred from direct assay
21685204 RGD
located in ciliary rootlet IDA
IDA: Inferred from direct assay
21685204 RGD
located in ciliary transition zone IDA
IDA: Inferred from direct assay
21685204 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase Nek4

  • NIMA (never in mitosis gene a)-related expressed kinase 4

  • NIMA (never in mitosis gene a)-related kinase 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-183068 AP4-43 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nek4 NCBI NCBI:6787