12 Results for "

dCMP

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "dCMP" in MCE Product Catalog:

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2'-Deoxycytidine-5'-monophosphate
2'-Deoxycytidine-5'-monophosphate
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1 Cited Publications
Cat. No.: HY-W009216
CAS No.: 1032-65-1
Synonyms: 5'-dCMP; Deoxy-CMP; 2'-Deoxycytidine-5'-monophosphoric acid
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection

2'-Deoxycytidine-5'-monophosphate (5'-dCMP) is a compound that binds to the adenovirus terminal protein with a molecular weight of 80000 daltons. 2'-Deoxycytidine-5'-monophosphate forms a covalent complex with this protein and is associated with adenovirus DNA replication .
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2'-Deoxycytidine-5'-monophosphoric acid disodium
2'-Deoxycytidine-5'-monophosphoric acid disodium
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1 Cited Publications
Cat. No.: HY-W011152
CAS No.: 13085-50-2
Synonyms: dCMP disodium
2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an endogenous metabolite .
Gemcitabine triphosphate trisodium
Gemcitabine triphosphate trisodium
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Cat. No.: HY-17026E
Synonyms: dFdCTP trisodium
Category:  

Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:  

Drug Metabolite DNA/RNA Synthesis Apoptosis

Gemcitabine triphosphate (dFdCTP) trisodium is the active metabolite of Gemcitabine (HY-17026). The mechanism of Gemcitabine triphosphate trisodium cell-killing is its competition with cytidine triphosphate during DNA replication, which results in the inhibition of chain elongation. Gemcitabine triphosphate trisodium shows a Ki of 11.2 μM against DNA polymerase α and 14.4 μM against DNA polymerase ε. Gemcitabine triphosphate trisodium partially inhibits dCMP deaminase and acts as a substrate for DNA synthesis to incorporate into cellular DNA and RNA. Gemcitabine triphosphate trisodium disrupts DNA and RNA synthesis, arrests cell cycle in G0/G1 and S phases, triggers apoptosis, reduces tumor cell proliferation. Gemcitabine triphosphate trisodium can be used for the research of pancreatic cancer and non-small cell lung cancer .
Gemcitabine triphosphate
Gemcitabine triphosphate
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Cat. No.: HY-17026A
CAS No.: 110988-86-8
Synonyms: dFdCTP
Category:  

Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:  

Drug Metabolite DNA/RNA Synthesis Apoptosis

Gemcitabine triphosphate (dFdCTP) is the active metabolite of Gemcitabine (HY-17026). The mechanism of Gemcitabine triphosphate cell-killing is its competition with cytidine triphosphate during DNA replication, which results in the inhibition of chain elongation. Gemcitabine triphosphate shows a Ki of 11.2 μM against DNA polymerase α and 14.4 μM against DNA polymerase ε. Gemcitabine triphosphate partially inhibits dCMP deaminase and acts as a substrate for DNA synthesis to incorporate into cellular DNA and RNA. Gemcitabine triphosphate disrupts DNA and RNA synthesis, arrests cell cycle in G0/G1 and S phases, triggers apoptosis, reduces tumor cell proliferation. Gemcitabine triphosphate can be used for the research of pancreatic cancer and non-small cell lung cancer .
2'-Deoxycytidine-5'-monophosphate (Standard)
2'-Deoxycytidine-5'-monophosphate (Standard)
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Cat. No.: HY-W009216R
CAS No.: 1032-65-1
Synonyms: 5'-dCMP (Standard); Deoxy-CMP (Standard); 2'-Deoxycytidine-5'-monophosphoric acid (Standard)
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

2'-Deoxycytidine-5'-monophosphoric acid (Standard) is the analytical standard of 2'-Deoxycytidine-5'-monophosphoric acid. This product is intended for research and analytical applications. 2'-Deoxycytidine-5'-monophosphate (2'-Deoxycytidine-5'-monophosphoric acid) is an endogenous metabolite. 2'-Deoxycytidine-5'-monophosphate is a deoxynucleotide building block of which DNA is made. 2'-Deoxycytidine-5'-monophosphate can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP and supports DNA biosynthesis .
2'-Deoxycytidine-5'-monophosphate-15N3
2'-Deoxycytidine-5'-monophosphate-15N3
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Cat. No.: HY-W009216S
Synonyms: 5'-dCMP-15N3; Deoxy-CMP-15N3; 2'-Deoxycytidine-5'-monophosphoric acid-15N3
2'-Deoxycytidine-5'-monophosphoric acid- 15N3 is the 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid . 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
2'-Deoxycytidine-5'-monophosphate-13C9 dilithium
2'-Deoxycytidine-5'-monophosphate-13C9 dilithium
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Cat. No.: HY-W009216S4
Synonyms: 5'-dCMP-13C9 dilithium; Deoxy-CMP-13C9 dilithium; 2'-Deoxycytidine-5'-monophosphoric acid-13C9 dilithium
2'-Deoxycytidine-5'-monophosphoric acid- 13C9 dilithium is the 13C-labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite .
5'-dCMPS
5'-dCMPS
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Cat. No.: HY-131813
CAS No.: 64145-27-3
Synonyms: 2'-Deoxycytidine-5'-O-monophosphorothioate
Target:  

Drug Derivative

Research Areas:  

Others

5'-dCMPS is an analogue of 5'-dCMP and a potential substrate, competitive inhibitor or regulator of enzymes that interact with 5'-dCMP .
Cytidylate kinase
Cytidylate kinase
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Cat. No.: HY-E70108
CAS No.: 37278-21-0
Target:  

PKC

Research Areas:  

Others

Cytidylate kinase catalyzes the phosphoryl transfer from ATP to CMP and dCMP, resulting in the formation nucleoside diphosphates .
2'-Deoxycytidine-5'-monophosphate-d12 dilithium
2'-Deoxycytidine-5'-monophosphate-d12 dilithium
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Cat. No.: HY-W009216S3
Synonyms: 5'-dCMP-d12 dilithium; Deoxy-CMP-d12 dilithium; 2'-Deoxycytidine-5'-monophosphoric acid-d12 dilithium
2'-Deoxycytidine-5'-monophosphoric acid-d12 dilithium is deuterium labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
2'-Deoxycytidine-5'-monophosphate-15N3,d12 dilithium
2'-Deoxycytidine-5'-monophosphate-15N3,d12 dilithium
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Cat. No.: HY-W009216S2
Synonyms: 5'-dCMP-15N3,d12 dilithium; Deoxy-CMP-15N3,d12 dilithium; 2'-Deoxycytidine-5'-monophosphoric acid-15N3,d12 dilithium
2'-Deoxycytidine-5'-monophosphoric acid- 15N3,d12 dilithium is deuterium and 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
2'-Deoxycytidine-5'-monophosphate-13C9,15N3 dilithium
2'-Deoxycytidine-5'-monophosphate-13C9,15N3 dilithium
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Cat. No.: HY-W009216S1
Synonyms: 5'-dCMP-13C9,15N3 dilithium; Deoxy-CMP-13C9,15N3 dilithium; 2'-Deoxycytidine-5'-monophosphoric acid-13C9,15N3 dilithium
2'-Deoxycytidine-5'-monophosphoric acid- 13C9, 15N3 dilithium is 13C and 15N-labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
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