20231-01-0
Chemical Structure
EWP 815
- CAS No.: 20231-01-0
- Formula:C12H22N4S4
- Molecular Weight:350.59
IUPAC Name: 4-methylpiperazine-1-carbothioic dithioperoxyanhydride
InChIKey: OOBDBFPYJXJEHC-UHFFFAOYSA-N
SMILES: S=C(N1CCN(C)CC1)SSC(N2CCN(C)CC2)=S
Biological Activity: EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins(1,4)P2 phosphatase and Ins(1,4,5)P3 5-phosphatase. EWP 815 also inhibits enzyme dopamine β-hydroxylase activity[1][2].
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EWP 815 | 99.15% | EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins(1,4)P2 phosphatase and Ins(1,4,5)P3 5-phosphatase. EWP 815 also inhibits enzyme dopamine β-hydroxylase activity. | ||||||||||||||||||||
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- [1]. Fowler CJ, et al. Inhibition of inositol 1,4,5-trisphosphate 5-phosphatase by micromolar concentrations of disulfiram and its analogues. Biochem J. 1993 Feb 1;289 ( Pt 3)(Pt 3):853-9. [Content Brief]
- [2]. Carlsson A, et al. On the beta-hydroxylation of (+-)-alpha-methyldopamine in vivo. Eur J Pharmacol. 1968 Dec;5(1):85-92. [Content Brief]
Keywords