132579-32-9
132579-32-9
Chemical Structure
Rocepafant
Synonym(s): BN 50730; LAU-8080
- No. CAS: 132579-32-9
- Formula:C26H23ClN6OS2
- Molecular Weight:535.08
IUPAC Name: 6-(2-chlorophenyl)-N-(4-methoxyphenyl)-1-methyl-7,10-dihydro-4H-pyrido[4',3':4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-9(8H)-carbothioamide
InChIKey: WBGAFGNZNGJVNW-UHFFFAOYSA-N
SMILES: S=C(N(C1)CCC2=C1SC3=C2C(C4=CC=CC=C4Cl)=NCC5=NN=C(C)N53)NC6=CC=C(OC)C=C6
Biological Activity: Rocepafant (BN 50730) is a specific platelet activating factor (PAF) antagonist. Rocepafant can be used in rheumatoid arthritis and nervous system research[1].
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Rocepafant | Rocepafant (BN 50730) is a specific platelet activating factor (PAF) antagonist. Rocepafant can be used in rheumatoid arthritis and nervous system research. | |||||||||||||||||||||
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References
- [1]. Silva CL,et al. Formation of a highly stable complex between BN 50730 [tetrahydro-4,7,8,10 methyl-1(chloro-2 phenyl)-6 (methoxy-4 phenyl-carbamoyl)-9 pyrido [4',3'-4,5] thieno [3,2-f] triazolo-1,2,4 [4,3-a] diazepine-1,4] and the platelet-activating factor receptor in rabbit platelet membranes. Biochem Pharmacol. 1996 Jan 26;51(2):193-6. [Content Brief]
Keywords
