1378976-02-3
1378976-02-3
Chemical Structure
MMG-0358
- No. CAS: 1378976-02-3
- Formula:C8H6ClN3O
- Molecular Weight:195.61
IUPAC Name: 4-chloro-2-(1H-1,2,3-triazol-5-yl)phenol
InChIKey: NBDFMTBYKCBTSW-UHFFFAOYSA-N
SMILES: ClC1=CC(C2=CN=NN2)=C(O)C=C1
Biological Activity: MMG-0358 is a potent IDO1 inhibitor. MMG-0358 shows IC50 values of 2 nM in a cellular assay on mIDO1, 80 nM in a cellular assay on hIDO1, 330 nM in an enzymatic assay on hIDO1 at pH 6.5, and 71 nM in an enzymatic assay on hIDO1 at pH 7.4[1].
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MMG-0358 | MMG-0358 is a potent IDO1 inhibitor. MMG-0358 shows IC50 values of 2 nM in a cellular assay on mIDO1, 80 nM in a cellular assay on hIDO1, 330 nM in an enzymatic assay on hIDO1 at pH 6.5, and 71 nM in an enzymatic assay on hIDO1 at pH 7.4. | |||||||||||||||||||||
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References
Keywords
