MYOM3 - myomesin 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 127294

About MYOM3

Cytogenetic location: 1p36.11 Genomic coordinates (GRCh38): 1:24,056,041-24,112,135 (from NCBI)

This gene has 4 transcripts (splice variants), 199 orthologues and 11 paralogues. Biased expression in heart (RPKM 41.6), kidney (RPKM 17.2) and 4 other tissues.

Summary

Predicted to enable actin filament binding activity and protein homodimerization activity. Predicted to be involved in muscle contraction. Predicted to be active in M band. [provided by Alliance of Genome Resources, Apr 2022]

MYOM3 Products (1)

mRNA Protein Name
NM_152372.4 NP_689585.3 myomesin-3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Referencias Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MYOM3 Protein Structure

I-set

I-set: Immunoglobulin I-set domain (156 - 246)

I-set

I-set: Immunoglobulin I-set domain (272 - 359)

fn3

fn3: Fibronectin type III domain (375 - 459)

fn3

fn3: Fibronectin type III domain (502 - 587)

fn3

fn3: Fibronectin type III domain (603 - 685)

fn3

fn3: Fibronectin type III domain (701 - 786)

fn3

fn3: Fibronectin type III domain (804 - 888)

Ig_2

Ig_2: Immunoglobulin domain (1033 - 1090)

Ig_2

Ig_2: Immunoglobulin domain (1130 - 1196)

I-set

I-set: Immunoglobulin I-set domain (1340 - 1424)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1437 a.a.
Protein Preferred Names Protein Names

myomesin-3

  • myomesin family, member 3

Related Diseases

Diseases Alias
Chronic Dacryocystitis
Acute Inflammation Of Lacrimal Passage
Dacryocystitis

  • Nasolacrimal Sac Infection
Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2d

  • Alpha-Sarcoglycanopathy

  • Dmda2

  • Duchenne-Like Autosomal Recessive Muscular Dystrophy Type 2

  • Lgmd2d

  • Muscular Dystrophy, Limb-Girdle, Type 2d

  • Primary Adhalinopathy
Tibial Muscular Dystrophy

  • Tmd

  • Udd Myopathy

  • Distal Titinopathy

  • Finnish Tibial Muscular Dystrophy

  • Tardive Tibial Muscular Dystrophy

  • Udd Type Distal Myopathy

  • Udd Distal Myopathy

  • Udd-Markesbery Muscular Dystrophy

  • Distal Myopathy, Udd Type

  • Distal Myopathies

  • Tibial Muscular Dystrophy, Tardive
Distal Arthrogryposis

  • Arthrogryposis Multiplex Congenita

  • Arthrogryposis

  • Congenital Multiple Arthrogryposis

  • Congenital Arthromyodysplasia

  • Fibrous Ankylosis Of Multiple Joints

  • Guerin-Stern Syndrome

  • Guérin-Stern Syndrome

  • Myodystrophia Fetalis Deformans

  • Otto Syndrome

  • Rocher-Sheldon Syndrome

  • Rossi Syndrome

  • Amc

  • Multiple Congenital Arthrogryposis

  • Arthrogryposis Syndrome

  • Arthrogryposis, Distal

  • Distal Arthrogryposis Syndrome

  • Freeman-Sheldon Syndrome

  • Arthrogryposis, Distal, Type 2b

  • Congenital Multiplex Arthrogryposis

  • Amyoplasia Congenita

  • Congenital Amyoplasia

  • Amc - [Arthrogryposis Multiplex Congenita]
Autosomal Recessive Limb-Girdle Muscular Dystrophy

  • Muscular Dystrophy, Limb-Girdle, Autosomal Recessive
Hypertrophic Cardiomyopathy

  • Hypertrophic Obstructive Cardiomyopathy

  • Cardiomyopathy, Hypertrophic

  • Cardiomyopathy Hypertrophic Obstructive

  • Cardiomyopathy, Hypertrophic, Familial

  • Idiopathic Myocardial Hypertrophy

  • Idiopathic Hypertrophic Cardiomyopathy

  • Obstructive Idiopathic Hypertrophic Cardiomyopathy

  • Obstructive Cardiomyopathy

  • Idiopathic Hypertrophic Subaortic Stenosis

  • Muscular Subaortic Stenosis

  • Hypertrophic Obstructive Subaortic Stenosis
Dilated Cardiomyopathy

  • Familial Dilated Cardiomyopathy

  • Primary Dilated Cardiomyopathy

  • Idiopathic Dilated Cardiomyopathy

  • Congestive Cardiomyopathy

  • Idiopathic Dilation Cardiomyopathy

  • Primary Familial Dilated Cardiomyopathy

  • Cardiomyopathy, Dilated

  • DCM

  • Cardiomyopathy, Familial Dilated

  • Dilated Cardiomyopathy, Familial

  • Hypokinetic Dilated Cardiomyopathy, Familial

  • Familial Idiopathic Cardiomyopathy

  • Fdc

  • Cardiomyopathy, Familial Idiopathic

  • Idiopathic Cardiomegaly

  • Dilated Congestive Cardiomyopathy

  • Chronic Dilated Cardiomyopathy

  • Ccm - [Congestive Cardiomyopathy]

  • Cocm - [Congestive Cardiomyopathy]

  • Dcm - [Dilated Cardiomyopathy]

  • Dilated-Hypokinetic Cardiomyopathy

  • Congestive Idiopathic Cardiomyopathy

  • Primary Idiopathic Dilated Cardiomyopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS08962 MYOM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MYOM3 MGD MGI:2685280
Rattus norvegicus MYOM3 RGD RGD:1310060
Macaca mulatta MYOM3 VGNC VGNC:75030
Felis catus MYOM3 VGNC VGNC:63692
Canis familiaris MYOM3 VGNC VGNC:43582
Bos taurus MYOM3 VGNC VGNC:31839