Dpm1 - dolichyl-phosphate mannosyltransferase subunit 1, catalytic Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 296394

Summary

Enables alcohol binding activity; dolichyl-phosphate beta-D-mannosyltransferase activity; and mannose binding activity. Involved in GDP-mannose metabolic process and dolichol metabolic process. Located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ie. Orthologous to human DPM1 (dolichyl-phosphate mannosyltransferase subunit 1, catalytic). [provided by Alliance of Genome Resources, Apr 2022]

Dpm1 Products (1)

mRNA Protein Name
NM_001106544.1 NP_001100014.1 dolichol-phosphate mannosyltransferase subunit 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables D-mannose binding IDA
IDA: Inferred from direct assay
2844175 RGD
enables alcohol binding IDA
IDA: Inferred from direct assay
2844175 RGD
enables dolichyl-phosphate beta-D-mannosyltransferase activity IDA
IDA: Inferred from direct assay
2844175 RGD
Biological Process GO Annotation Evidence References Source
involved in GDP-mannose metabolic process IDA
IDA: Inferred from direct assay
2844175 RGD
involved in dolichol metabolic process IDA
IDA: Inferred from direct assay
2844175 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dolichol-phosphate mannosyltransferase subunit 1

  • dolichol-phosphate (beta-D) mannosyltransferase 1

  • dolichyl-phosphate mannosyltransferase 1

  • dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03958 DPM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22147 Dpm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28668 Dpm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dpm1 NCBI NCBI:8813