Vapb - VAMP associated protein B and C Gene

Also Known as VAP-B; VAMP-B

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60431

Summary

Predicted to enable several functions, including FFAT motif binding activity; protein dimerization activity; and tubulin binding activity. Predicted to be involved in several processes, including IRE1-mediated unfolded protein response; endoplasmic reticulum organization; and modulation by host of viral genome replication. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Predicted to be active in endoplasmic reticulum membrane and plasma membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 8; autosomal dominant adult-onset proximal spinal muscular atrophy; and spinal muscular atrophy. Orthologous to human VAPB (VAMP associated protein B and C). [provided by Alliance of Genome Resources, Apr 2022]

Vapb Products (1)

mRNA Protein Name
NM_021847.4 NP_068619.1 vesicle-associated membrane protein-associated protein B

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence Referencias Source
is active in endoplasmic reticulum IDA
IDA: Inferred from direct assay
30841933 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
30841933 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
30841933 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
30841933 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicle-associated membrane protein-associated protein B

  • VAMP (vesicle-associated membrane protein)-associated protein B and C

  • VAMP-associated protein B

  • vesicle-associated membrane protein, associated protein B and C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS15603 VAPB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18156 Vapb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24630 Vapb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vapb NCBI NCBI:9217