KLLN - killin, p53 regulated DNA replication inhibitor Gene

Also Known as CWS4; KILLIN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100144748

About KLLN

Cytogenetic location: 10q23.31 Genomic coordinates (GRCh38): 10:87,859,158-87,863,533 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 13 orthologues and is associated with 3 phenotypes.

Summary

The protein encoded by this intronless gene is found in the nucleus, where it can inhibit DNA synthesis and promote S phase arrest coupled to Apoptosis. The expression of this DNA binding protein is upregulated by transcription factor p53. [provided by RefSeq, Dec 2012]

KLLN Products (1)

mRNA Protein Name
NM_001126049.2 NP_001119521.1 killin
Protein Preferred Names Protein Names

killin

KLLN Antibodies

Cat. No. Product Name Application Reactivity
HY-P83399 Killin Antibody (YA3144) WB Human, Mouse, Rat
HY-P83399A Killin Antibody (YA3144)(PBS only) WB Human, Mouse, Rat

Related Diseases

Diseases Alias
Cowden Syndrome 4

  • CWS4

  • Cowden Syndrome, Type 4
Cowden Syndrome

  • Cowden Disease

  • Multiple Hamartoma Syndrome

  • Cowden'S Disease

  • Lhermitte-Duclos Disease

  • Cd

  • Cs

  • Mham

  • Dysplastic Gangliocytoma Of Cerebellum

  • Cowden'S Syndrome

  • Hamartoma Syndrome, Multiple
Hereditary Breast Cancer

  • Familial Breast Cancer

  • Familial Breast Carcinoma

  • Hereditary Breast Carcinoma
Cowden Syndrome 1

  • Bannayan-Riley-Ruvalcaba Syndrome

  • Pten Hamartoma Tumor Syndrome

  • Lhermitte-Duclos Disease

  • Bannayan-Zonana Syndrome

  • Phts

  • Riley-Smith Syndrome

  • Bzs

  • Ruvalcaba-Myhre-Smith Syndrome

  • Multiple Hamartoma Syndrome

  • Rmss

  • Brrs

  • Dysplastic Gangliocytoma Of The Cerebellum

  • CWS1

  • Cs

  • Cd

  • Mham

  • Pten Hamartoma Tumor Syndrome With Granular Cell Tumor

  • Macrocephaly Multiple Lipomas And Hemangiomata

  • Bannayan-Ruvalcaba-Riley Syndrome

  • Myhre-Riley-Smith Syndrome

  • LDD

  • Cerebelloparenchymal Disorder Vi

  • Hamartoma Syndrome, Multiple

  • Bbrs

  • Macrocephaly, Pseudopapilledema, And Multiple Hemangiomata

  • Macrocephaly, Multiple Lipomas, And Hemangiomata

  • Macrocephaly Pseudopapilledema And Multiple Hemangiomas

  • Ruvalcaba -Myhre-Smith Syndrome

  • Ruvalcaba-Myhre Syndrome

  • Cowden Disease

  • Macrocephaly Pseudopapilledema And Multiple Hemangiomata

  • Cerebellar Granule Cell Hypertrophy And Megalencephaly

  • Cpd6

  • Pten Hamartoma Tumor Syndromes

  • Cowden Syndrome, Type 1
Infiltrating Angiolipoma

  • Angiolipoma, Infiltrating
Gangliocytoma

  • Ganglioneuroma

  • Gangliocytoma Of Central Nervous System
Liver Inflammatory Pseudotumor

  • Inflammatory Pseudotumor Of The Liver

  • Liver Inflammatory Myofibroblastic Tumor
Multinodular Goiter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07389 KLLN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus KLLN RGD RGD:7720631
Others KLLN NCBI