PYURF - PIGY upstream open reading frame Gene

Homo sapiens

Also known as PREY; NDUFAFQ

Gene ID: 100996939 | Gene type: protein coding

About PYURF

Cytogenetic location: 4q22.1 Genomic coordinates (GRCh38): 4:88,520,998-88,523,776 (from NCBI)

This gene has 1 transcript (splice variant) and 214 orthologues. Ubiquitous expression in adrenal (RPKM 45.6), fat (RPKM 42.6) and 25 other tissues.

Summary

The product of this gene, which is well-conserved, is encoded by the same bicistronic transcript that encodes phosphatidylinositol glycan anchor biosynthesis, class Y, but the two proteins are unrelated. This gene represents the protein encoded by the upstream open reading frame, while the protein encoded by the downstream open reading frame is represented by GeneID:84992. [provided by RefSeq, Aug 2012]

PYURF Products(1)

mRNA	Protein	Name
NM_032906.5	NP_116295.1	protein preY, mitochondrial precursor

PYURF Protein Structure

Trm112p

0
100
114 a.a.

Protein Preferred Names

Protein Names

protein preY, mitochondrial

NADH:ubiquinone oxidoreductase complex assembly factor Q

Related Diseases

Diseases

Alias

Hyperphosphatasia With Mental Retardation Syndrome 6

Hyperphosphatasia With Intellectual Disability Syndrome 6	HPMRS6
Glycosylphosphatidylinositol Biosynthesis Defect 12	Gpibd12
Hyperphosphatasia With Mental Retardation Syndrome, Type 6

Mitochondrial Disease

Mitochondrial Diseases

Mitochondrial Disorder

Gaucher Disease, Type Ii

GD2	Gd Ii
Gaucher Disease, Acute Neuronopathic Type	Gaucher Disease Type 2
Gaucher Disease Type Ii	Gaucher'S Disease Type Ii
Infantile Cerebral Gaucher Disease	Acute Neuronopathic Gaucher Disease
Gd 2	Gaucher Disease, Infantile Cerebral
Gaucher Disease 2	Type 2 Gaucher Disease
Gaucher Disease, Type 2

Otosclerosis

Otospongiosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11496	PYURF Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	PYURF	VGNC	VGNC:57410
Rattus norvegicus	PYURF	RGD	RGD:1565524
Mus musculus	PYURF	MGD	MGI:1913709

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