country

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

FAM13A - family with sequence similarity 13 member A Gene

Also Known as FAM13A1; ARHGAP48

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 10144

About FAM13A

Cytogenetic location: 4q22.1 Genomic coordinates (GRCh38): 4:88,725,960-89,057,185 (from NCBI)

This gene has 22 transcripts (splice variants), 238 orthologues, 2 paralogues and is associated with 1 phenotype. Ubiquitous expression in fat (RPKM 21.4), thyroid (RPKM 14.6) and 25 other tissues.

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytosol. Implicated in chronic obstructive pulmonary disease. [provided by Alliance of Genome Resources, Apr 2022]

FAM13A Products (5)

mRNA	Protein	Name
NM_001015045.3	NP_001015045.1	protein FAM13A isoform b
NM_001265578.2	NP_001252507.1	protein FAM13A isoform c
NM_001265579.2	NP_001252508.1	protein FAM13A isoform d
NM_001265580.2	NP_001252509.1	protein FAM13A isoform e
NM_014883.4	NP_055698.2	protein FAM13A isoform a

FAM13A Protein Structure

RhoGAP

0
200
400
600
800
1023 a.a.

Protein Preferred Names	Protein Names
protein FAM13A	FAM13A1_v2 protein

Related Diseases

Diseases	Alias
Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease	Polycystic Kidney Disease 2 PKD2 Polycystic Kidney Disease, Adult, Type Ii Apkd2 Polycystic Kidney Disease, Type 2 Adpkd2 Adult Polycystic Kidney Disease Type 2 Autosomal Dominant Polycystic Kidney Disease 2 Pkd-2 Polycystic Kidney Disease Adult Type Ii Polycystic Kidney Type 2 Autosomal Dominant Disease Kidney Disease, Polycystic, Type 2
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To Cryptogenic Fibrosing Alveolitis ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Silicosis	Silicotuberculosis Acute Silicosis Chronic Silicosis Pneumoconiosis Due To Silicates Silica Pneumoconiosis Silicotic Fibrosis Of Lung Accelerated Silicosis Experimental Silicosis
Bronchitis	Chronic Bronchitis Acute Bronchitis Bronchitis, Chronic Acute Bronchitis And Bronchiolitis Chest Cold Chest Infection Ci - Chest Infection Recurrent Wheezy Bronchitis Bronchitis Chronic Lower Respiratory Tract Infection Acute Lower Respiratory Tract Infection Chronic Bronchitis Nos Senile Bronchitis Bronchitis Nos In Those Under L5 Years Of Age Bronchitis Nos
Plasma Protein Metabolism Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04686	FAM13A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	FAM13A	VGNC	VGNC:62063
Rattus norvegicus	FAM13A	RGD	RGD:1309807
Bos taurus	FAM13A	VGNC	VGNC:28731
Macaca mulatta	FAM13A	VGNC	VGNC:72299
Mus musculus	FAM13A	MGD	MGI:1889842
Canis familiaris	FAM13A	VGNC	VGNC:40596