SFTA3 - surfactant associated 3 Gene

Homo sapiens

Also known as SPH; SP-H; NANCI; PAHRF; SFTPH

Gene ID: 253970 | Gene type: ncRNA

About SFTA3

Cytogenetic location: 14q13.3 Genomic coordinates (GRCh38): 14:36,473,288-36,519,556 (from NCBI)

This gene has 10 transcripts (splice variants). Restricted expression toward lung (RPKM 71.4).

Summary

Involved in wound healing. Located in cytoplasm and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in wound healing	IMP IMP: Inferred from mutant phenotype	29955092	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	24743970	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	24743970	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Diseases

Diseases

Alias

Choreoathetosis And Congenital Hypothyroidism With Or Without Pulmonary Dysfunction

Brain-Lung-Thyroid Syndrome	Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress
CAHTP	Blt Syndrome
Choreoathetosis-Hypothyroidism-Neonatal Respiratory Distress Syndrome	Choreoathetosis-Hypothyroidism-Neonatal Respiratory Distress
Brain-Thyroid-Lung Syndrome	Chreoathetosis And Congenital Hypothyroidism With Or Without Pulmonary Dysfunction

Chorea, Benign Hereditary

Benign Hereditary Chorea	BHC
Chorea, Hereditary Benign	Benign Familial Chorea
Bch	Hereditary Progressive Chorea Without Dementia
Chorea Familial Benign	Hereditary Chorea Without Dementia
Chorea Benign Hereditary	Bche Deficiency
Chorea, Hereditary, Benign	Chorea, Benign Familial

Thyroid Cancer, Nonmedullary, 1

Papillary Thyroid Carcinoma	Familial Nonmedullary Thyroid Cancer, Papillary
Nonmedullary Thyroid Carcinoma, Papillary	Papillary Thyroid Cancer
NMTC1	Papillary Carcinoma Of Thyroid
Pact	Thyroid Carcinoma, Papillary
Non-Medullary Thyroid Carcinoma	Thyroid Cancer, Non-Medullary, 1
Familial Non-Medullary Thyroid Cancer	Fnmtc
Nmtc	Nonmedullary Thyroid Carcinoma
Ptc	Tpc
Thyroid Papillary Carcinoma	Cancer, Thyroid, Nonmedullary
Cancer, Thyroid, Nonmedullary, Type 1	Thyroid Carcinoma, Nonmedullary 1
Familial Nonmedullary Thyroid Gland Carcinoma	Papillary Carcinoma, Diffuse Sclerosing, Thyroid Gland

Nkx2-1-Related Disorders

Nkx2-1-Related Disorder

Central Corneal Ulcer

Spherocytosis, Type 5

Hereditary Spherocytosis Type 5	SPH5
Hs5	Spherocytosis, Hereditary, 5
Hereditary Spherocytosis 5	Spherocytosis 5
Spherocytosis, Hereditary, Type 5

Spherocytosis, Type 2

Hereditary Spherocytosis Type 2	SPH2
Spherocytosis, Hereditary, 2	Hs2
Hereditary Spherocytosis 2	Spherocytosis 2
Spherocytosis, Type 2, Autosomal Dominant

Plasma Cell Neoplasm

Plasma Cell Dyscrasia	Paraproteinemias
Plasma Cell Tumour	Plasmacytic Tumor
Multiple Myeloma	Plasmacytoma
Plasma Cell Tumours	Plasma Cells Dyscrasia

Anisometropia

Spherocytosis, Type 3

Hereditary Spherocytosis Type 3	SPH3
Hs3	Spherocytosis, Hereditary, 3
Hereditary Spherocytosis 3	Spherocytosis 3

Regular Astigmatism

Spherocytosis, Type 1

Hereditary Spherocytosis Type 1	SPH1
Hs1	Spherocytosis, Hereditary, 1
Sph	Hs
Hereditary Spherocytosis 1	Spherocytosis 1

Myeloma, Multiple

Multiple Myeloma	Plasma Cell Myeloma
Kahler Disease	Myelomatosis
Medullary Plasmacytoma	Multiple Myeloma, Resistance To
Myeloma	Plasma Cell Dyscrasia
Kahler'S Disease	Multiple Myeloma, Susceptibility To
Myeloma - Multiple	Kahler-Bozzolo Disease
Plasma Cell Myelomas	MM
Plasma Cell Neoplasm	Primary Systemic Amyloidosis
Primary Amyloidosis	Immunoglobulin Deposition Disease
Plasmacytic Myeloma	Multiple Myelomata
Multiple Myeloma Nos	Multiple Myeloma Without Mention Of Remission
Monostotic Plasma Cell Myeloma	Mm - [Multiple Myeloma]

Cancerophobia

Cancer Phobia

Fear Of Getting Cancer

Nosophobia

Secondary Corneal Edema

Eye Disease

Eye Diseases	Abnormality Of The Eye
Toxoplasma Oculopathy

Refractive Error

Refractive Errors

Brown-Sequard Syndrome

Brown-Squard Syndrome	Hemicord Syndrome
Hemiparaplegic Syndrome	Hemispinal Cord Syndrome
Brown-Séquard Syndrome

Esotropia

Convergence In Manifest Squint	Crossed Eyes
Internal Strabismus	Convergent Concomitant Strabismus
Convergent Squint	Convergent Strabismus
Cross-Eye

Flying Phobia

Aerophobia

Macular Degeneration, Age-Related, 4

Age Related Macular Degeneration 4	ARMD4
Macular Degeneration, Age-Related, Type 4

Macular Degeneration, Age-Related, 1

Macular Degeneration	Age-Related Macular Degeneration
Macular Degeneration, Age-Related	Age Related Macular Degeneration
Age Related Macular Degeneration 1	ARMD1
Senile Macular Degeneration	Maculopathy, Age-Related, 1
Macular Degeneration, Age-Related, Reduced Risk Of	Age Related Maculopathy 1
Age Related Maculopathies	Age Related Maculopathy
Senile Macular Retinal Degeneration	Macular Degeneration Of Retina
Age-Related Maculopathy	Amd
Armd	Age-Related Maculopathy, Susceptibility To
Maculopathy Age-Related	Macular Degeneration, Age-Related, 1, Susceptibility To
Maculopathy, Age-Related	Macular Degeneration, Age-Related, Type 1
Macular Degeneration, Age-Related, 2

Stargardt Disease

Stargardt Disease 1	Stargardt Macular Dystrophy
Stargardt Disease-1	Juvenile Onset Macular Degeneration
Stargardt Macular Degeneration	Juvenile Macular Degeneration
Macular Dystrophy With Flecks, Type 1	Stgd
Fundus Flavimaculatus	Stargardt 1
Stargardts Disease

Night Blindness

Nyctalopia

Amblyopia

Lazy Eye

Achromatopsia

Achm	Rod Monochromatism
Total Color Blindness	Rod Monochromacy
Monochromatism	Achromatism
Complete Or Incomplete Color Blindness	Pingelapese Blindness
Achromatopsia 1	Achromatopsia 2
Achromatopsia 3

Hereditary Spherocytosis

Congenital Spherocytic Hemolytic Anemia	Spherocytic Anemia
Congenital Spherocytosis	Spherocytosis, Type 1
Minkowski Chauffard Syndrome	Hs
Minkowski-Chauffard Disease	Minkowski-Chauffard Syndrome
Spherocytosis Hereditary	Spherocytosis, Hereditary
Anemia, Hereditary Spherocytic Hemolytic

Cone Dystrophy

Retinal Cone Dystrophy	Dystrophy, Cone
Cone Dystrophy 3

Eye Degenerative Disease

Congenital Stationary Night Blindness

Night Blindness, Congenital Stationary	Congenital Essential Nyctalopia
Oguchi Disease	Blindness, Night, Stationary, Congenital

Leber Plus Disease

Leber Congenital Amaurosis	Lca
Leber'S Amaurosis	Leber'S Disease
Amaurosis Congenita Of Leber	Amaurosis Congenita Of Leber, Type 1
Lhon Plus Disease	Congenital Absence Of The Rods And Cones
Congenital Retinal Blindness	Crb
Congenital Amaurosis Of Retinal Origin	Leber'S Congenital Amaurosis
Leber Congenital Amaurosis 1	Leber'S Congenital Tapetoretinal Degeneration
Leber'S Congenital Tapetoretinal Dysplasia	Lca1
Leber Congenital Amaurosis Type 1	Retinal Blindness, Congenital
Amaurosis, Leber Congenital	Dysgenesis Neuroepithelialis Retinae
Hereditary Epithelial Dysplasia Of Retina	Hereditary Retinal Aplasia
Heredoretinopathia Congenitalis	Leber Abiotrophy
Leber Congenital Tapetoretinal Degeneration	Lebers Congenital Amaurosis
Optic Atrophy, Hereditary, Leber

Usher Syndrome

Deafness-Retinitis Pigmentosa Syndrome	Dystrophia Retinae Pigmentosa-Dysostosis Syndrome
Graefe-Usher Syndrome	Hallgren Syndrome
Usher'S Syndrome	Retinitis Pigmentosa-Deafness Syndrome
Retinitis Pigmentosa-Hearing Loss Syndrome	Ush
Usher Syndromes

Fundus Dystrophy

Retinal Dystrophy	Retinal Dystrophies
Dystrophy, Retinal

Strabismus

Strabismus, Susceptibility To	Strabismus, Susceptibility To, 1
Strabismus 1

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Bardet-Biedl Syndrome

Bbs	Biedl-Bardet Syndrome

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12759	SF3A3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS12779	SFTA2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown