Alx1 - ALX homeobox 1 Gene

Rattus norvegicus

Also known as Cart1; CART1X

Gene ID: 25401 | Gene type: protein coding

About Alx1

Summary

Enables DNA-binding transcription factor activity and protein homodimerization activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of transcription, DNA-templated. Located in nucleus. Orthologous to human ALX1 (ALX homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Alx1 Products(1)

mRNA	Protein	Name
NM_012921.1	NP_037053.1	ALX homeobox protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
NOT enables DNA binding	IMP IMP: Inferred from mutant phenotype	12390248	RGD
enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	12390248	RGD
enables DNA-binding transcription factor activity	IMP IMP: Inferred from mutant phenotype	12929931	RGD
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	12390248	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	12390248	RGD
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	12929931	RGD
involved in positive regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	12390248	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	12390248	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ALX homeobox protein 1

CART-1	cartilage homeo protein 1
cartilage homeoprotein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00636	ALX1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Alx1	NCBI	NCBI:8092

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