mt-Atp6 - ATP synthase 6, mitochondrial Gene

Rattus norvegicus (strain: BN/SsNHsdMCW)

Also known as ATP6

Gene ID: 26197 | Gene type: protein coding

About mt-Atp6

Summary

Predicted to contribute to proton-transporting ATP Synthase activity, rotational mechanism. Involved in aging and response to hyperoxia. Predicted to be integral component of membrane. Predicted to be part of mitochondrial proton-transporting ATP Synthase complex. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; NARP syndrome; Parkinson's disease; multiple sclerosis; and systemic lupus erythematosus. Orthologous to human MT-ATP6 (mitochondrially encoded ATP Synthase membrane subunit 6). [provided by Alliance of Genome Resources, Apr 2022]

mt-Atp6 Products(1)

mRNA	Protein	Name
YP_665634.1 ATP synthase F0 subunit 6 (mitochondrion) [Rattus norvegicus]

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in response to hyperoxia	IEP IEP: Inferred from expression pattern	18481000	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ATPase subunit 6

ATP synthase F0 subunit 6

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08751	MT-ATP6 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	mt-Atp6	NCBI	NCBI:4508

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