2. Gene
  3. Rp1l1 - retinitis pigmentosa 1 homolog like 1 Gene

Rp1l1 - retinitis pigmentosa 1 homolog like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Dcdc4; Rp1hl1

Gene ID: 271209 | Gene type: protein coding

About Rp1l1

Summary

This gene encodes a member of the doublecortin family. This protein is a retinal-specific protein. It contains two N-terminal doublecortin domains, which can assemble and stabilize axonemal microtubules, but lacks the C-terminal repetitive regions including the 16aa repeat found in human RP1L1. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. [provided by RefSeq, Sep 2010]

Rp1l1 Products(1)

mRNA Protein Name
NM_146246.3 NP_666358.2 retinitis pigmentosa 1-like 1 protein
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in photoreceptor cell development IMP
IMP: Inferred from mutant phenotype
19657028 MGI
involved in photoreceptor cell maintenance IMP
IMP: Inferred from mutant phenotype
19657028 MGI
Cellular Component GO Annotation Evidence Reference Source
located in axoneme IDA
IDA: Inferred from direct assay
19657028 MGI
located in photoreceptor connecting cilium IDA
IDA: Inferred from direct assay
19657028 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
19657028 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinitis pigmentosa 1-like 1 protein

retinitis pigmentosa 1-like protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12139 RP1L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rp1l1 NCBI NCBI:94137