2. Gene
  3. Ofd1 - Ofd1 centriole and centriolar satellite protein Gene

Ofd1 - Ofd1 centriole and centriolar satellite protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1562231

Gene ID: 302661 | Gene type: protein coding

About Ofd1

Summary

Predicted to enable alpha-tubulin binding activity; gamma-tubulin binding activity; and identical protein binding activity. Involved in cilium assembly. Predicted to be located in centriolar satellite; centriole; and cilium. Predicted to be active in centrosome; ciliary basal body; and motile cilium. Biomarker of retinal degeneration. Human ortholog(s) of this gene implicated in Joubert syndrome 10; Simpson-Golabi-Behmel syndrome type 2; orofaciodigital syndrome I; retinitis pigmentosa; and retinitis pigmentosa 23. Orthologous to human OFD1 (OFD1 centriole and centriolar satellite protein). [provided by Alliance of Genome Resources, Apr 2022]

Ofd1 Products(2)

mRNA Protein Name
NM_001106961.1 NP_001100431.1 oral-facial-digital syndrome 1 protein
NM_001106961.1 NP_001100431.1 oral-facial-digital syndrome 1 protein
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
27196396 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oral-facial-digital syndrome 1 protein

oral-facial-digital syndrome 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09756 OFD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ofd1 NCBI NCBI:8481