Slc46a1 - solute carrier family 46 member 1 Gene

Rattus norvegicus

Also known as rPCFT; RGD1309472

Gene ID: 303333 | Gene type: protein coding

About Slc46a1

Summary

Enables folic acid transmembrane transporter activity. Involved in folic acid transport. Located in brush border membrane. Biomarker of chronic kidney disease. Human ortholog(s) of this gene implicated in hereditary folate malabsorption. Orthologous to human SLC46A1 (solute carrier family 46 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc46a1 Products(1)

mRNA	Protein	Name
NM_001013969.1	NP_001013991.1	proton-coupled folate transporter

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in brush border membrane	IDA IDA: Inferred from direct assay	23287122	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

proton-coupled folate transporter

PCFT/HCP1	heme carrier protein 1
solute carrier family 46 (folate transporter), member 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13260	SLC46A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc46a1	NCBI	NCBI:113235

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