Kcnq4 - potassium voltage-gated channel, subfamily Q, member 4 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 60613

Summary

Enables voltage-gated Potassium Channel activity. Acts upstream of or within inner ear morphogenesis; potassium ion transport; and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated Potassium Channel complex. Predicted to be integral component of membrane. Is expressed in heart; utricle; and utricle epithelium. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 2A and sensorineural hearing loss. Orthologous to human KCNQ4 (potassium voltage-gated channel subfamily Q member 4). [provided by Alliance of Genome Resources, Apr 2022]

Kcnq4 Products (1)

mRNA Protein Name
NM_001081142.3 NP_001074611.1 potassium voltage-gated channel subfamily KQT member 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables voltage-gated potassium channel activity IMP
IMP: Inferred from mutant phenotype
16437162 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within inner ear morphogenesis IMP
IMP: Inferred from mutant phenotype
16437162 MGI
acts upstream of or within potassium ion transport IMP
IMP: Inferred from mutant phenotype
16437162 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
16437162 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium voltage-gated channel subfamily KQT member 4

  • KQT-like 4

  • potassium channel subunit alpha KvLQT4

  • voltage-gated potassium channel subunit Kv7.4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122114 ICA-27243 Activator 98.74% Unkown
HY-18063 ML252 Inhibitor 99.9% Unkown
HY-123264 RL648_81 Inhibitor 99.49% Unkown
HY-18063A ML252 hydrochloride Inhibitor 98.5% Unkown
HY-182435 CLE-030 Agonist / Unkown
HY-RS07176 KCNQ4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-115823 ztz240 / Unkown
HY-RS18392 Kcnq4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24873 Kcnq4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnq4 NCBI NCBI:9132