TSPYL1 - TSPY like 1 Gene

Also Known as TSPYL

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 7259

About TSPYL1

Cytogenetic location: 6q22.1 Genomic coordinates (GRCh38): 6:116,274,858-116,279,930 (from NCBI)

This gene has 2 transcripts (splice variants), 232 orthologues, 18 paralogues and is associated with 2 phenotypes.

Summary

The protein encoded by this gene is found in the nucleolus and is similar to that of a family of genes on the Y-chromosome. This gene is intronless. Defects in this gene are a cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT). [provided by RefSeq, Dec 2009]

TSPYL1 Products (1)

mRNA	Protein	Name
NM_003309.4	NP_003300.1	testis-specific Y-encoded-like protein 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables enzyme binding	IPI IPI: Inferred from physical interaction	23382074	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TSPYL1 Protein Structure

NAP

0
100
200
300
400
437 a.a.

Protein Preferred Names	Protein Names
testis-specific Y-encoded-like protein 1	TSPY-like protein 1

Related Diseases

Diseases	Alias
Sudden Infant Death With Dysgenesis Of The Testes Syndrome	SIDDT Sudden Infant Death-Dysgenesis Of The Testes Syndrome Sudden Infant Death - Dysgenesis Of The Testes
Sudden Infant Death Syndrome	SIDS Sudden Infant Death Syndrome, Susceptibility To Cot Death Crib Death Sudden Death Of Nonspecific Cause In Infancy Sudden Infant Death Death, Sudden, Syndrome, Infant
Mixed Germ Cell-Sex Cord Neoplasm	Mixed Germ Cell-Sex Cord-Stromal Tumor Mixed Germ Cell-Sex Cord Tumor
Yunis-Varon Syndrome	Cleidocranial Dysplasia With Micrognathia, Absent Thumbs, And Distal Aphalangia Yunis Varon Syndrome YVS Cleidocranial Dysplasia-Micrognathia-Absent Thumbs Syndrome Cleidocranial Dysplasia, Micrognathia, Absent Thumbs, & Distal Aphalangia Yunis-Varón Syndrome
Fetal Hemoglobin Quantitative Trait Locus 1	Hereditary Persistence Of Fetal Hemoglobin Delta-Beta-Thalassemia Delta-Beta Thalassemia Delta Beta-Thalassemia HBFQTL1 Hemoglobin F, Hereditary Persistence Of Hpfh Hereditary Persistence Of Fetal Hemoglobin, Hb Gene Cluster-Related Hemoglobin, Fetal, Quantitative Trait Locus 1 Hereditary Persistence Of Fetal Hemoglobin Thalassemia Hpfh - [Hereditary Persistence Of Fetal Haemoglobin] Fetal Haemoglobin Persistence Of Fetal Haemoglobin Persistent Haemoglobin F
Gastroesophageal Reflux	Gastroesophageal Reflux Disease Gerd GER Gastroesophageal Reflux, Pediatric Acid Reflux Gastresophageal Reflux Gastro-Esophageal Reflux Gerd - Gastro-Esophageal Reflux Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15181	TSPYL1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TSPYL1	RGD	RGD:1307726
Mus musculus	TSPYL1	MGD	MGI:1298395
Bos taurus	TSPYL1	VGNC	VGNC:53811
Macaca mulatta	TSPYL1	VGNC	VGNC:104437