PRCD - photoreceptor disc component Gene

Also Known as RP36

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 768206

About PRCD

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:76,527,586-76,553,580 (from NCBI)

This gene has 13 transcripts (splice variants), 66 orthologues and is associated with 3 phenotypes. Ubiquitous expression in fat (RPKM 1.8), adrenal (RPKM 1.0) and 23 other tissues.

Summary

This gene is predominantly expressed in the retina, and mutations in this gene are the cause of autosomal recessive retinal degeneration in both humans and dogs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

PRCD Products (1)

mRNA Protein Name
NM_001077620.3 NP_001071088.1 photoreceptor disk component PRCD precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
24992209 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
24992209 GOA
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
24992209 GOA
located in extracellular region IDA
IDA: Inferred from direct assay
24992209 GOA
located in photoreceptor outer segment membrane IDA
IDA: Inferred from direct assay
27613864 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRCD Protein Structure

Rod_cone_degen

Rod_cone_degen: Progressive rod-cone degeneration (1 - 54)

  • 0
  • 54 a.a.
Protein Preferred Names Protein Names

photoreceptor disk component PRCD

  • progressive rod-cone degeneration protein

Related Diseases

Diseases Alias
Retinitis Pigmentosa 36

  • RP36

  • Retinitis Pigmentosa-36

  • Retinitis Pigmentosa, Type 36
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Cone-Rod Dystrophy 2

  • Cone-Rod Dystrophy

  • CORD2

  • Cone-Rod Retinal Dystrophy

  • Rcrd2

  • Cone-Rod Retinal Dystrophy 2

  • Crd2

  • Cord

  • Crd

  • Retinal Cone-Rod Dystrophy

  • Cone-Rod Retinal Dystrophy-2

  • Retinal Cone-Rod Dystrophy 2

  • Tapetoretinal Degeneration

  • Cone-Rod Degeneration

  • Cone Rod Dystrophy

  • Dystrophy, Cone-Rod

  • Dystrophy, Cone-Rod, Type 2

  • Retinitis Pigmentosa

  • Retinitis Pigmentosa 2

  • Progressive Cone-Rod Dystrophy
Fundus Dystrophy

  • Retinal Dystrophy

  • Retinal Dystrophies

  • Dystrophy, Retinal
Ichthyosis, Congenital, Autosomal Recessive 10

  • Autosomal Recessive Congenital Ichthyosis 10

  • ARCI10

  • Ichthyosis, Congenital, Autosomal Recessive, Type 10
Cone-Rod Dystrophy 1

  • CORD1

  • Crd1

  • Cone-Rod Retinal Dystrophy-1

  • Retinitis Pigmentosa 1
Macular Degeneration, X-Linked Atrophic

  • X-Linked Atrophic Macular Degeneration

  • Macular Degeneration, X-Linked, Atrophic

  • MDXLA

  • Degeneration, Macular, X-Linked Atrophic
Retinitis Pigmentosa 17

  • RP17

  • Retinitis Pigmentosa-17

  • Retinitis Pigmentosa, Type 17
Corneal Dystrophy, Posterior Amorphous

  • Posterior Amorphous Corneal Dystrophy

  • PACD

  • Chromosome 12q21.33 Deletion Syndrome

  • Posterior Amorphous Stromal Dystrophy
Ceroid Lipofuscinosis, Neuronal, 5

  • Neuronal Ceroid Lipofuscinosis 5

  • CLN5

  • Cln5 Disease

  • Finnish Variant Late Infantile Neuronal Ceroid Lipofuscinosis

  • Vlincl

  • Ceroid Lipofuscinosis, Neuronal, 5, Variable Age At Onset

  • Neuronal Ceroid Lipofuscinosis 5 Variable Age Of Onset

  • Cln5 Disease, Adult

  • Cln5 Disease, Juvenile

  • Cln5 Disease, Late Infantile

  • Neuronal Ceroid Lipofuscinosis Finnish Variant

  • Finnish Vlincl

  • Jansky-Bielschowsky Disease

  • Late-Infantile Neuronal Ceroid Lipofuscinosis

  • Neuronal Ceroid Lipofuscinosis, Late-Infantile

  • Finnish

  • Neuronal Ceroid Lipofuscinosis 5 With Variable Age At Onset

  • Lipofuscinosis, Ceroid, Neuronal, Type 5

  • Late-Infantile Neuronal Ceroid Lipfuscinosis

  • Ceroid Lipofuscinosis, Neuronal, 6
Retinal Degeneration

  • Degeneration Of Retina
Chronic Interstitial Cystitis
Bestrophinopathy, Autosomal Recessive

  • Bestrophinopathy

  • Autosomal Recessive Bestrophinopathy

  • ARB

  • Bestrophinopathies

  • Retinopathy, Burgess-Black Type

  • Retinopathy Burgess-Black Type
Late-Onset Retinal Degeneration

  • LORD

  • Retinal Degeneration, Late-Onset, Autosomal Dominant

  • Autosomal Dominant Late-Onset Retinal Degeneration

  • Pigmentary Retinopathy

  • Retinal Degeneration, Late-Onset

  • Retinitis Pigmentosa
Sveinsson Chorioretinal Atrophy

  • SCRA

  • Atrophia Areata

  • Helicoid Peripapillary Chorioretinal Degeneration

  • Hpcd

  • Aa

  • Peripapillary Chorioretinal Degeneration, Icelandic Type

  • Helicoidal Peripapillary Chorioretinal Degeneration

  • Atrophy, Chorioretinal, Sveinsson
Achromatopsia

  • Achm

  • Rod Monochromatism

  • Total Color Blindness

  • Rod Monochromacy

  • Monochromatism

  • Achromatism

  • Complete Or Incomplete Color Blindness

  • Pingelapese Blindness

  • Achromatopsia 1

  • Achromatopsia 2

  • Achromatopsia 3
Eye Degenerative Disease
Leber Plus Disease

  • Leber Congenital Amaurosis

  • Lca

  • Leber'S Amaurosis

  • Leber'S Disease

  • Amaurosis Congenita Of Leber

  • Amaurosis Congenita Of Leber, Type 1

  • Lhon Plus Disease

  • Congenital Absence Of The Rods And Cones

  • Congenital Retinal Blindness

  • Crb

  • Congenital Amaurosis Of Retinal Origin

  • Leber'S Congenital Amaurosis

  • Leber Congenital Amaurosis 1

  • Leber'S Congenital Tapetoretinal Degeneration

  • Leber'S Congenital Tapetoretinal Dysplasia

  • Lca1

  • Leber Congenital Amaurosis Type 1

  • Retinal Blindness, Congenital

  • Amaurosis, Leber Congenital

  • Dysgenesis Neuroepithelialis Retinae

  • Hereditary Epithelial Dysplasia Of Retina

  • Hereditary Retinal Aplasia

  • Heredoretinopathia Congenitalis

  • Leber Abiotrophy

  • Leber Congenital Tapetoretinal Degeneration

  • Lebers Congenital Amaurosis

  • Optic Atrophy, Hereditary, Leber
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11057 PRCD Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PRCD VGNC VGNC:33286
Rattus norvegicus PRCD RGD RGD:6488422
Canis familiaris PRCD VGNC VGNC:44942
Mus musculus PRCD MGD MGI:3649529
Macaca mulatta PRCD VGNC VGNC:104643
Felis catus PRCD VGNC VGNC:99324