TMEM38A - transmembrane protein 38A Gene

Also Known as TRICA; TRIC-A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79041

About TMEM38A

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:16,661,139-16,690,023 (from NCBI)

This gene has 3 transcripts (splice variants), 205 orthologues and 1 paralogue. Broad expression in brain (RPKM 7.4), stomach (RPKM 6.7) and 21 other tissues.

Summary

Predicted to enable Potassium Channel activity. Predicted to act upstream of or within several processes, including cellular response to caffeine; inorganic cation transmembrane transport; and regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

TMEM38A Products (1)

mRNA Protein Name
NM_024074.4 NP_076979.1 trimeric intracellular cation channel type A

TMEM38A Protein Structure

TRIC

TRIC: TRIC channel (37 - 233)

  • 0
  • 100
  • 200
  • 299 a.a.
Protein Preferred Names Protein Names

trimeric intracellular cation channel type A

Related Diseases

Diseases Alias
Osteogenesis Imperfecta, Type Xiv

  • Osteogenesis Imperfecta Type 14

  • OI14

  • Osteogenesis Imperfecta Type Xiv

  • Oi, Type Xiv

  • Osteogenesis Imperfecta 14

  • Oi Type Xiv

  • Oi-Xiv
King-Denborough Syndrome

  • King Denborough Syndrome

  • King Syndrome

  • Kousseff Nichols Syndrome

  • KDS

  • Noonan Like Contracture Myopathy Hyperpyrexia

  • Anesthetic-Induced Malignant Hyperpyrexia In Children

  • Koussef-Nichols Syndrome
Myopathy, X-Linked, With Postural Muscle Atrophy

  • Emery-Dreifuss Muscular Dystrophy 6, X-Linked

  • XMPMA

  • X-Linked Myopathy With Postural Muscle Atrophy

  • X-Linked Emery-Dreifuss Muscular Dystrophy 6

  • EDMD6

  • Emd6
Muscular Dystrophy, Congenital, Lmna-Related

  • Congenital Muscular Dystrophy

  • Congenital Muscular Dystrophy Due To Lmna Mutation

  • MDCL

  • L-Cmd

  • Lmna-Related Congenital Muscular Dystrophy

  • Muscular Dystrophy, Congenital

  • Congenital Muscular Dystrophy Lmna-Related

  • Lmna-Related Cmd

  • Cmd

  • Mdc

  • Muscular Dystrophy Congenital Lmna-Related

  • Dystrophy, Muscular, Congenital, Lmna-Related

  • Dystrophy, Muscular, Congenital

  • Hereditary Muscular Dystrophy

  • Congenital Hereditary Muscular Dystrophy

  • Congenital Progressive Muscular Dystrophy

  • Hereditary Progressive Muscular Dystrophy
Ectodermal Dysplasia 9, Hair/Nail Type

  • ECTD9

  • Ectodermal Dysplasia 9

  • Dysplasia, Ectodermal, Type 9, Hair/Nail
Keratosis Follicularis Spinulosa Decalvans

  • Kfsd

  • Keratosis Follicularis Spinulosa Decalvans Cum Ophiasi

  • Keratosis Follicularis Spinulosa Decalvans, X-Linked

  • Keratosis Follicularis Spinulosa Decalvans, Autosomal Dominant
Keratosis Pilaris Atrophicans

  • KPA

  • Burnett Schwartz Berberian Syndrome
Emery-Dreifuss Muscular Dystrophy

  • Edmd

  • Emery-Dreifuss Syndrome

  • Muscular Dystrophy, Emery-Dreifuss

  • Humeroperoneal Neuromuscular Disease

  • Muscular Dystrophy, Tardive, Dreifuss-Emery Type, With Contractures

  • Scapuloperoneal Syndrome, X-Linked

  • Benign Scapuloperoneal Muscular Dystrophy With Early Contractures

  • Muscular Dystrophy, Emery-Dreifuss Type

  • Muscular Dystrophy Emery-Dreifuss

  • Dystrophy, Muscular, Emery-Dreifuss

  • Emd - [Emery-Dreifuss Muscular Dystrophy]
Cardiomyopathy, Dilated, 1h

  • Dilated Cardiomyopathy 1h

  • Dilated Cardiomyopathy With Conduction Defect

  • CMD1H

  • Cardiomyopathy, Dilated, With Conduction Defect
Brittle Bone Disorder

  • Osteogenesis Imperfecta

  • Brittle Bone Disease

  • Fragilitas Ossium

  • Osteopsathyrosis

  • Lobstein Disease

  • Oi

  • Vrolik Disease

  • Lobstein'S Disease

  • Lobstein'S Syndrome

  • Vrolik'S Disease

  • Porak And Durante Disease

  • Glass Bone Disease

  • Osteogenesis Imperfecta, Dominant Perinatal Lethal

  • Osteogenesis Imperfecta, Recessive Perinatal Lethal

  • Brittle Bone Syndrome

  • Oi - [Osteogenesis Imperfecta]

  • Ossium Fragility

  • Osteitis Fragilitans

  • Bony Fragility

  • Blue Sclera With Fragility Of Bone And Deafness

  • White Blue Sclera - Fragility Of Bone - Deafness
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14719 TMEM38A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TMEM38A RGD RGD:1307901
Canis familiaris TMEM38A VGNC VGNC:47574
Mus musculus TMEM38A MGD MGI:1921416
Felis catus TMEM38A VGNC VGNC:66341
Bos taurus TMEM38A VGNC VGNC:36080
Others TMEM38A NCBI