Slc26a5 - solute carrier family 26, member 5 Gene

Also Known as Pres; prestin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80979

Summary

Enables spectrin binding activity. Acts upstream of or within regulation of membrane potential. Located in basolateral plasma membrane; lateral plasma membrane; and lateral wall of outer hair cell. Is expressed in brain; cochlea; embryo; and organ of Corti. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 61. Orthologous to human SLC26A5 (solute carrier family 26 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc26a5 Products (3)

mRNA Protein Name
NM_001289787.1 NP_001276716.1 prestin isoform 2
NM_001289788.1 NP_001276717.1 prestin isoform 3
NM_030727.5 NP_109652.3 prestin isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18796539 MGI
enables spectrin binding IDA
IDA: Inferred from direct assay
18796539 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of membrane potential IDA
IDA: Inferred from direct assay
12584604 MGI
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
12584604 MGI
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
18796539 MGI
located in lateral wall of outer hair cell IDA
IDA: Inferred from direct assay
25748314 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
24303013 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prestin

  • outer hair cell motor protein

  • prestin (motor protein)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13139 SLC26A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc26a5 NCBI NCBI:375611