2243737-33-7
2243737-33-7
Chemical Structure
Cetagliptin
- CAS No.: 2243737-33-7
- Formula:C18H21F6N4O5P
- Molecular Weight:518.35
SMILES: O=P(O)(O)O.FC(F)(C1=NC=C2N1CCN(C(C[C@H](N)CC3=C(C=C(C(F)=C3)F)F)=O)[C@@H]2C)F
Biological Activity: Cetagliptin is an orally active inhibitor for dipeptidyl peptidase 4 (DPP-4) and CYP2D6 (IC50 of 6 µM). Cetagliptin is a substrate for P-glycoprotein. Cetagliptin reduces the GLP-1 degradation, maintains the level of postprandial blood sugar, and can be used in type 2 diabetes mellitus research[1].
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Cetagliptin | Cetagliptin is an orally active inhibitor for dipeptidyl peptidase 4 (DPP-4) and CYP2D6 (IC50 of 6 µM). Cetagliptin is a substrate for P-glycoprotein. Cetagliptin reduces the GLP-1 degradation, maintains the level of postprandial blood sugar, and can be used in type 2 diabetes mellitus research. | |||||||||||||||||||||
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References
Keywords
